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WebNov 2, 2024 · CCRK, also known as CDK20, is the latest identified member of the CDK family, which exerts both cell-cycle-dependent and cell-cycle-independent functions. When aberrantly expressed, CCRK drives... Webthat CCRK is widely expressed in cell lines originating from a variety of tumor tissues, and CCRK suppression would cause cell cycle arrest at the G0-G1 phase by decreasing the phosphorylation of Cdk2/ Rb (11,17,21,23). In addition, CCRK is overexpressed in a number of human malignancies. Mouse models of CCRK functions have provided data suggesting spanish speakers in the classroom
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