Dysregulation of lipid metabolism
WebJul 29, 2024 · Autophagy modulates major pathological changes, including hepatic lipid metabolism, inflammation, and fibrosis, suggesting the potential of modulating autophagy … Serum concentrations of 483 lipids from COVID-19 patients were processed by multivariate analysis using MetaboAnalyst 4.0 (http://www.metaboanalyst.ca)49,50,51. The lipidic dataset was imputed to remove the missing values, log(2)-transformed and scaled according to … See more A Regione-Campania-cohort of 53 patients with a diagnosis of COVID-19 (SARS-CoV-2 infection) admitted at one of the following hospitals was … See more Serum lipidome content was investigated by mass spectrometry-based targeted metabolomics41,42. The lipidomic platform was set to … See more The serum adiponectin concentrations were measured by enzyme-linked immunosorbent assay (ELISA) as previously reported21. … See more Concentrations of TSLP protein in blood serum were evaluated by enzyme-linked immunosorbent assay (ELISA) (Human TSLP Uncoated ELISA … See more
Dysregulation of lipid metabolism
Did you know?
WebMar 9, 2024 · 1. Introduction. Asthma is characterized by airway hyper-responsiveness, mucus hypersecretion, infiltration of the airway by eosinophils and type 2 (T2) immune … WebInhibition of HIF-2α protein reversed lipid metabolism dysregulation induced by acute hypoxia in HepG2 cells, which suggested that HIF-2α signaling may be relevant to oxygen …
WebAccumulation of IHTG is likely due to an imbalance between fatty acid delivery, synthesis and removal (via oxidation or export as TAG) from the liver; insulin plays a key role in all … WebAltogether, research in the field of pulmonary fibrosis continues to suggest that metabolic dysregulation acts as a key contributor to the pathogenesis of the disease, and that drugs targeting different aspects of cellular metabolism, including glycolysis, mitochondrial oxygen consumption, and lipid metabolism, should be strongly considered for ...
WebAug 30, 2024 · Alterations in lipid metabolism are an important metabolic rewiring phenomenon for malignant cells to maintain their rapid proliferation in the hypoxic …
WebWe used bioinformatic analysis and examined changes in lipid metabolism in HCC cells in response to matrix stiffness. Moreover, ACADL was identified as a key enzyme, initiating the FAO process, modulated by matrix stiffness. Lipid metabolic reprogramming influenced by matrix stiffness was interacted in an ACADL-dependent mechanoresponsive manner.
WebApr 24, 2024 · Then, metabolism dysregulations were investigated in both patients and murine models. Alterations of elongase and desaturase activities were observed along … cicc client account regulationsWebMay 13, 2024 · Recently, accumulating evidence suggests that lipid metabolism alteration is closely related to drug resistance in tumor. Targeting lipid metabolism in combination with traditional chemotherapeutic drugs is a promising strategy to overcome drug resistance. dgn kongress 2023 abstractWebThree molecules play key roles in the regulation of triglyceride metabolism: apolipoprotein C-III(ApoC-III), angiopoietin-like protein 4(ANGPLT4), and lipoprotein lipase(LPL). The aim of … cic captains of innovationWebJun 9, 2024 · Frontiers Dysregulation of Lipid Metabolism in Macrophages Is Responsible for Severe Endotoxin Tolerance in FcgRIIB-Deficient Lupus Mice View Article Impact … ciccarello madonna of humilityWebOct 21, 2016 · Hypercaloric diets lead to the dysregulation of multiple lipid metabolic pathways, which contributes to the onset and progression of metabolic disease. cicc cashewWebAug 23, 2016 · Lipid metabolism disorders, such as Gaucher disease and Tay-Sachs disease, involve lipids. Lipids are fats or fat-like substances. They include oils, fatty acids, … dgn leitlinie myasthenia gravisWebApr 11, 2024 · A further aspect of lipid dysregulation promoting PD pathogenesis is oxidative stress and inflammation, with proinflammatory lipid mediators such as platelet … ciccarelli white psychology 5th edition