Impact of hypoxia on cervical cancer outcomes
WitrynaCervical cancer (CC) is one of the most common gynecological malignancies worldwide, with nearly 570,000 new CC cases and more than 311,000 deaths every year. 1 In … WitrynaHypoxia-inducible factor-1α induces multidrug resistance protein in colon cancer ... Decreased pretreatment lymphocyte/monocyte ratio is associated with poor prognosis in stage Ib1–IIa cervical cancer patients who undergo radical surgery. Chen L, Zhang F, Sheng XG, Zhang SQ ... The impact of IGF-1R expression on the outcomes of …
Impact of hypoxia on cervical cancer outcomes
Did you know?
Witryna27 paź 2024 · The consequences of hypoxia on tumour biology and patient outcomes have therefore led to the investigation of strategies that can alleviate hypoxia in cancer cells, with the aim of... Witryna3 cze 2024 · Many reports have confirmed that hypoxia is a prognosis factor associated with adverse outcomes in cervical cancer [ 11 – 13 ]. Several hypoxia-related …
Witryna16 sie 2016 · Substantial data confirm the presence of hypoxia in many types of human tumors, although with considerable heterogeneity among individual tumors. Various approaches have been investigated for eliminating the hypoxic population. WitrynaNational Center for Biotechnology Information
Witryna26 kwi 2024 · Tumour hypoxia is a well-known adverse factor for the outcome of radiotherapy. For cervical tumours in particular, several studies indicate large … Witryna1 gru 2024 · 3.1. Hypoxia in cancer. Hypoxia is defined by a response to an imbalanced oxygen level in the environment, occurring due to either high consumption or low …
Witryna12 kwi 2024 · The metabolic enzymes involved in one-carbon metabolism are closely associated with tumor progression and could be potential targets for cancer therapy. Recent studies showed that serine hydroxymethyltransferase 2 (SHMT2), a crucial enzyme in the one-carbon metabolic pathway, plays a key role in tumor proliferation …
Witryna17 sty 2024 · Hypoxia is a predominant feature and HIF-1 pathway plays an very important role in cervical cancer, as well as a wide range of solid tumor [ 15, 16, 17 ]. csc academy helplineWitryna3 cze 2024 · Background: Hypoxia is a common microenvironment condition in most malignant tumors and has been shown to be associated with adverse outcomes of … dysart\u0027s newburgh meWitryna1 mar 2008 · The telomeric repeat amplification protocol (TRAP) assay revealed that hypoxia activated telomerase in cervical cancer ME180 cells, with peak induction at … csc ace reviewerWitrynaStudies of tumor hypoxia involving the direct assessment of the oxygenation status have suggested worse disease-free survival for patients with hypoxic cervical cancers or … csc.acscustomerservices lancashire.gov.ukWitrynaTumor hypoxia is a common feature of the microenvironment in solid tumors, primarily due to an inadequate, and heterogeneous vascular network. It is associated with … dysart\\u0027s newburgh maineWitryna3 lip 2024 · For describing a hypoxia cervical cancer risk factor model, 200 genes related to the hypoxia pathway downloaded from MSigDB for analysis. The TCGA-TPM data of cervical cancer samples were divided into high and low expression groups according to the median of gene expression and a cox analysis as based on OS (the … csc accredited trainingWitrynadc.contributor.author: Datta, Anubhav: dc.contributor.author: West, Catharine M L: dc.contributor.author: O'Connor, James P B: dc.contributor.author: Choudhury, … csc accredited training institutions 2023